Combining Blood Gene Expression and Cellfree DNA to Diagnose Subclinical Rejection in Kidney Transplant Recipients

Clinical Journal of the American Society of Nephrology, octubre de 2021, https://doi.org/10.2215/CJN.05530421

Sookhyeon Park, Kexin Guo, Raymond L. Heilman, Emilio D. Poggio, David J. Taber, Christopher L. Marsh, Sunil M. Kurian, Steve Kleiboeker, Juston Weems, John Holman, Lihui Zhao, Rohita Sinha, Susan Brietigam, Christabel Rebello, Michael M. Abecassis and John J. Friedewald.


Octubre de 2021


 

The Real-life Experience of Developing and Commercializing TruGraf, a Validated Non-invasive Transplant Biomarker

Journal of Biochemistry and Analytical Studies, mayo de 2020, http://dx.doi.org/10.16966/2576-5833.123

M Roy First, Steven B Kleiboeker , Stanley Rose , John J Friedewald , and Michael M Abecassis.


Febrero de 2021


 

Kidney Graft Surveillance Biopsy Utilization and Trends: Results From a Survey of High-Volume Transplant Centers

Transplantation Proceedings, junio de 2020, https://doi.org/10.1016/j.transproceed.2020.04.1816

Darren M. Lee, Michael M. Abecassis, John J. Friedewald, Stanley Rose, and M. Roy First.


Junio de 2020


 

Discovery and Validation of a Novel Blood‐Based Molecular Biomarker of Rejection following Liver Transplantation

American Journal of Transplantation 30 de abril de 2020 https://doi.org/10.1111/ajt.15953

Josh Levitsky, Sumeet K. Asrani, Thomas Schiano, Adyr Moss, Kenneth Chavin, Charles Miller, Kexin Guo, Lihui Zhao, Manoj Kandpal, Nancy Bridges, Merideth Brown, Brian Armstrong, Sunil Kurian, Anthony J. Demetris, Michael Abecassis, The Clinical Trials in Organ Transplantation – 14 Consortium


Mayo de 2020


 

Outpatient Management of the Kidney Transplant Recipient during the SARS-CoV-2 Virus Pandemic

CJASN abril de 2020, CJN.04510420; DOI: https://doi.org/10.2215/CJN.04510420

Shana E. Gleeson, Richard N. Formica and Ethan P. Marin


Mayo de 2020


 

Serial Peripheral Blood Gene Expression Profiling to Assess Immune Quiescence in Kidney Transplant Recipients with Stable Renal Function

Ann Transplant publicado el: 28 de abril de 2020 DOI: 10.12659/AOT.920839

  1. Ram Peddi, Parul S. Patel, Courtney Schieve, Stan Rose, M. Roy First

Mayo de 2020


 

A Practical Guide to the Clinical Implementation of Biomarkers for Subclinical Rejection Following Kidney Transplantation

Transplantation: Abril de 2020 – Volumen 104 – Edición 4 – p 700-707 doi: 10.1097/TP.0000000000003064

Maarten Naesens MD PhD, John Friedewald MD, Valeria Mas MD PhD, Bruce Kaplan MD, Michael M. Abecassis MD MBA


Noviembre de 2019


 

Application of TruGraf v1: A Novel Molecular Biomarker for Managing Kidney Transplant Recipients With Stable Renal Function

Transplantation Proceedings Volumen 51, Edición 3, abril de 2019, Páginas 722-728

C.L. Marsh, S.M. Kurian, J.C. Rice, T.C. Whisenant, J. David, S. Rose, C. Schieve, D. Lee, J. Case, B. Barrick, V.R. Peddi, R.B. Mannon, R. Knight, D. Maluf, D. Mandelbrot, A. Patel, J.J. Friedewald, M.M. Abecassis, and M.R. First,


Abril de 2019


 

Investigator Assessment of the Utility of the TruGraf Molecular Diagnostic Test in Clinical Practice

Transplant Proc. abril de 2019;51(3):729-733. doi: 10.1016/j.transproceed.2018.10.024

First MR, Peddi VR, Mannon R, Knight R, Marsh CL, Kurian SM, Rice JC, Maluf D, Mandelbrot D, Patel A, David J, Schieve C, Lee D, Lewis P, Friedewald JJ, Abecassis MM, Rose S


Abril de 2019


 

Development and Clinical validity of a novel blood-based molecular biomarker for sub-clinical acute rejection following kidney transplant

American Journal of Transplantation Primera publicación: 9 de julio de 2018 https://doi.org/10.1111/ajt.15011

John J. Friedewald1, Sunil M. Kurian, Raymond L. Heilman, Thomas C. Whisenant, EmilioD. Poggio, Christopher Marsh, Prabhakar Baliga MD, Jonah Odim, Merideth M. Brown, David N. Ikle, Brian D. Armstrong, jane I. charette, Susan S. Brietigam, Nedjema Sustento-Reodica, Lihui Zhao, Manoj Kandpal, Daniel R. Salomon†, and Michael M. Abecassis*(ORCID 0000-0001-9333-463X), for the Clinical Trials in Organ Transplantation08 (CTOT-08)


Julio de 2018


 

Value of the TruGraf Blood Test as a Biomarker for Monitoring Renal Transplant Recipients

Insights in Biomedicine ISSN 2572-5610, abril de 2018, vol.3 No.2:8

First MR, Rose S, Schieve C, Lee D, Lewis P, Pierry D, David J, McNulty M, Clark D, Weiss G, Kurian S, Whisenant T, Friedewald JJ and Abecassis MM


Abril de 2018


 

Clinical Utility of Peripheral Blood Gene Expression Profiling in Kidney Transplant Recipients to Assess the Need for Surveillance Biopsies in Subjects with Stable Renal Function

Journal of Transplant Technology & Research, noviembre de 2017, 7:3

Martin Roy First, Thomas Whisenant, John J Friedewald, Stan Rose, Darren, Lee, Sunil Kurian, Dierdra Pierry, Peter Lewis, Terri Gelbart, Michael M Abecassis


Noviembre de 2017


 

An Economic Analysis of the Cost Effectiveness of Blood Gene Expression Profiling in Kidney Transplant Recipients

Journal of Health & Medical Economics, julio de 2017, ISSN 2471-9927 vol.3, 1:3

Roy First M, Darren Lee, Peter Lewis and Stan Rose


Julio de 2017


 

Analytical and Clinical Validation of a Molecular Diagnostic Signature in Kidney Transplant Recipients

Journal of Transplantation Technologies & Research, septiembre de 2017, 7:3

Martin Roy First, Deirdre Pierry, Michael McNulty, Sunil M Kurian, Stan Rose, Thomas Whisenant, Terri Gelbart, April Venzon, Nadia Bayat, Peter Lewis, John J Friedewald, Michael M Abecassis and Darren Lee


Julio de 2017


 

Biomarker Guidelines for High-Dimensional Genomic Studies in Transplantation: Adding Method to the Madness

Transplantation, marzo de 2017 Volumen 101 Número 3

Sunil M. Kurian, PhD, Thomas Whisenant, PhD, Valeria Mas, PhD, Raymond Heilman, MD, Michael Abecassis, MD, Daniel R. Salomon, MD, Adyr Moss, MD, and Bruce Kaplan, MD


Marzo de 2017


 

Orthogonal Comparison of Molecular Signatures of Kidney Transplants With Subclinical and Clinical Acute Rejection: Equivalent Performance Is Agnostic to Both Technology and Platform

American Journal of Transplantation enero de 2017; 17: 2103 – 2116

  1. M. Kurian, E. Velazquez, R. Thompson, T. Whisenant, S. Rose, N. Riley, F. Harrison, T. Gelbart, and J. J. Friedewald, J. Charette, S. Brietigam, J. Peysakhovich, M. R. First, M. M. Abecassis and D. R. Salomon

Enero de 2017


 

Gene Expression in Biopsies of Acute Rejection and Interstitial Fibrosis/Tubular Atrophy Reveals Highly Shared Mechanisms That Correlate with Worse Long-Term Outcomes

Am J Transplant 2016; XX: 1-17

  1. D. Modena, S. M. Kurian SM, L. W. Gaber, J. Waalen, A. I. Su, T. Gelbart, T.S. Mondala, S. R. Head, S. Papp, R. Heilman, J. J. Friedewald, S. M. Flechner, C.L. Marsh, R.S. Sung, H. Shidban, L. Chan, M. M. Abecassis, D. R. Salomon

Marzo de 2016


 

Advancing Transplantation In Silico: Studying Global Gene Expression Using Functional Genomics for Transplantation Research

Textbook of Organ Transplantation (pp. 208-218). Chichester, Inglaterra: Wiley-Blackwell (2014)

Head SR, Kurian SM, Salomon DR


Julio de 2014


 

Molecular Classifiers for Acute Kidney Transplant Rejection in Peripheral Blood by Whole Genome Gene Expression Profiling

Am J Transplant 2014; 5(14):1164-1172

Kurian SM, Williams AN, Gelbart T, Campbell D, Mondala TS, Head SR, Horvath S, Gaber L, Thompson R, Whisenant T, Lin W, Langfelder P, Robison EH, Schaffer RL, Fisher JS, Friedewald J, Flechner SM, Chan LK, Wiseman AC, Shdban H, Mendez R, Heilman R, Abecassis MM, March CL, Salomon DR


Abril de 2014


 

Library Construction for Next-generation Sequencing: Overviews and Challenges

Biotechniques, febrero de 2014; 56:61-77

Head SR, Komori HK, LaMere SA, Whisenant T, Van Nieuwerburgh F, Salomon DR, Ordoukhanian P


Febrero de 2014


 

Genomic Biomarkers Correlate with HLA-Identical Renal Transplant Tolerance

J Am Soc Nephrol 2013;24(9):1376-1385

Leventhal JR, Mathew JM, Salomon DR, Kurian SM, Suthanthiran M, Tambur A, Friedewald J, Gallon L, Charette J, Levitsky J, Kanwar Y, Abecassis M, Miller J


Junio de 2013


 

Genomic meta-analysis of growth factor and integrin pathways in chronic kidney transplant injury

BMC Genomics 2013;14:275

Dosanjh A, Robison E, Mondala T, Head SR, Salomon DR, Kurian SM


Abril de 2013


 

The costimulatory immunogen LPS induces the B-Cell clones that infiltrate transplanted human kidneys

Proc Natl Acad Sci U S A 2012;109(16): 6036-6041

Grover RK, Cheng J, Peng Y, Jones TM, Ruiz DI, Ulevitch RJ, Glass JI, Dennis EA, Salomon DR, Lerner RA


Abril de 2012


 

Ectopic B-cell clusters that infiltrate transplanted human kidneys are clonal

Proc Natl Acad Sci U S A 2011;108(14):5560-5565

Cheng J, Torkamani A, Grover RK, Jones TM, Ruiz DI, Schork NJ, Quigley MM, Hall FW, Salomon DR, Lerner RA


Abril de 2011


 

Molecular mechanisms of chronic kidney transplant rejection via large-scale proteogenomic analysis of tissue biopsies

J Am Soc Nephrol 2010;21(2):362-373

Nakorchevsky A, Hewel JA, Kurian SM, Mondala TS, Campbell D, Head SR, Marsh CL, Yates JR III, Salomon DR


Enero de 2010


 

Biomarkers for early and late stage chronic allograft nephropathy by proteogenomic profiling of peripheral blood

PLoS One 2009;4(7):e6212

Kurian SM, Heilman R, Mondala TS, Nakorchevsky A, Hewel JA, Campbell D, Robison EH, Wang L, Lin W, Gaber L, Solez K, Shidban H, Mendez R, Schaffer RL, Fisher JS, Flechner SM, Head SR, Horvath S, Yates JR III, Marsh CL, Salomon DR


Julio de 2009


 

Kidney transplantation with sirolimus and mycophenolate mofetil-based immunosuppression: 5-year results of a randomized prospective trial compared to calcineurin inhibitor drugs

Am J Transplant 2004;4(9):1475-1489

Flechner SM, Kurian SM, Head SR, Sharp SM, Whisenant TC, Zhang J, Chismar JD, Horvath S, Mondala T, Gilmartin T, Cook DJ, Kay SA, Walker JR, Salomon DR


Abril de 2007


 

De novo kidney transplantation without use of calcineurin inhibitors preserves renal structure and function at two years

Am J Transplant 2004;4(11):1776-1785

Flechner SM, Kurian SM, Solez K, Cook DJ, Burke JT, Rollin H, Hammond JA, Whisenant T, Lanigan CM, Head SR, Salomon DR